HINZE CLAUDIA DR.,AULENBACHER OTTO,SUNDERMANN BERND DR.,OBERBORSCH STEFAN DR.,FRIEDERICHS ELMAR DR.,ENGLBERGER WERNER DR.,KOGEL BABETTE-YVONNE DR.,LINZ KLAUS DR.,SCHICK HANS DR. PROF.,SONNENSCHEIN HEL,Hinze Claudia Dr.,Aulenbacher Otto,Sundermann Bernd Dr.,Oberborsch Stefan Dr.,Friederichs Elmar Dr.
申请号：
SI200332314
公开号：
SI2062898T1
申请日:
2003.11.05
申请国别(地区):
SI
年份:
2013
代理人:
摘要：
Spiro-((4-amino-cyclohexane)-1,1'-1',3',4',9'-tetrahydropyrano-(3,4-b)-indole) derivatives (I) are new. Spiro-cyclic cyclohexylamine derivatives of formula (I), optionally in the form of racemates, pure stereoisomers (especially enantiomers or diastereomers) or their mixtures in all proportions, including free bases, free acids, salts (specifically acid or base addition salt) or solvates (specifically hydrates), are new. R1, R2 = H, optionally unsaturated, optionally mono- or polysubstituted 1-4C alkyl or CHO； R3 = -(CH2)n-Aryl； n = 0-2； R4 = H, optionally unsaturated, optionally mono- or polysubstituted 1-3C alkyl or -CO-(CH2)m-H； m = 0-2； R5 - R8 = H； 1-5C alkyl or 1-3C alkoxy (both optionally unsaturated and optionally mono- or polysubstituted)； or halo, OH, SH, SMe, OMe, NH2, COOH, COOMe, NHMe, NMe2 or NO2.
