A kind of Corydalis extract for anti-tachyarrhythmia, the extract prepared by the following method:Corydalis crude powder 100 parts by weight, is extracted by 60-80% ethanol 600-1000 parts by volume in 1-3 times, combined filtrate, concentrated under reduced pressure to a fluidextract of the relative density of 0.2 - 0.5g/mL; take the processed D101 resin, and the fluidextract prepared through the resin column with the flow rate of 0.2 - 0.5mL/min, impurity of deionized water with the flow rate of 0.2 - 0.5mL/min, 60-90% ethanol elution, flow rate 0.4 - 0.8mL/min, and recover ethanol, concentrate to Corydalis extract dry paste. According to the conventional method of adding conventional accessories, made into clinically acceptable pills, capsules, granules, tablets, oral liquid or injection. The extract has obvious effect on anti-arrhythmia.