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CYCLICAL OLIGOPEPTIDE, USE OF CYCLICAL OLIGOPEPTIDE, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PRODUCING A CYCLICAL OLIGOPEPTIDE.
专利权人:
LEXCICON LIMITED
发明人:
ROGER NEW
申请号:
BRPI0716891
公开号:
BRPI0716891A2
申请日:
2007.09.20
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
An internally-constrained cyclic oligopeptide comprising a ring of at least six amino acids for specifically binding to a target ligand, wherein the ring comprises a plurality of amino acid domains, each domain comprising at least two epitope-forming amino acids, and two or more associating functional groups positioned so that they form one or more intra-cyclic associations; whereby the cyclic oligopeptide is constrained in a single conformation so that the epitope-forming amino acids form an epitope in each domain, each epitope being capable of specifically binding to a target ligand.
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