您的位置: 首页 > 农业专利 > 详情页

Fused bicyclic compound
专利权人:
Yoichi Takahashi
发明人:
Yoichi Takahashi,Nobumasa Awai,Hidenori Akatsuka,Takayuki Kawaguchi,Toru Iijima
申请号:
US12671479
公开号:
US08258131B2
申请日:
2008.07.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a novel fused bicyclic compound having an affinity to a receptor of mineral corticoid (MR), shown by the formula [I]:wherein the ring A is a benzene ring having a substituent R1, fused to an adjacent 6-membered heterocyclic ring and further optionally having a substituent(s) other than R1, R1 is an alkylsulfonylamino group etc.,R2 and R3 are (a) the same of different and a hydrogen atom, an alkyl group or a substituted or unsubstituted aryl group, (b) combined each other to form an oxo group or (c) combined each other at its terminal together with the adjacent carbon atom to form a cycloalkyl group,X is a group of ═N—, ═C(R4)— or —CH(R4)—,R4 is (a) a hydrogen atom, (b) a cyano group, (c) a halogen atom, (d) an alkyl group, (e) an alkenyl group, (f) a cycloalkyl group (g) an alkanoyl group, (h) a carbamoyl group or (i) a cycloalkenyl group,Ar is an optionally substituted aromatic cyclic group anda dotted line means presence or absence of a double bond,or a pharmaceutically acceptable salt thereof,which is useful as an antihypertensive agent etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充