A disposable staple cartridge for a surgical cutting and fastening instrument. Various embodiments include a disposable anvil that is supported relative to the cartridge body and movable between open and closed positions. At least one tissue stop is provided on the disposable anvil for orienting the tissue to be cut and stapled relative to the staples supported within the cartridge body. Other embodiments relate to end effectors for surgical cutting and fastening instruments that can be used in connection with a plurality of staple cartridge bodies that each have a common length but which may different lengths of staple lines.
