An end effector, comprising: a frame comprising a first end and a second end； an anvil comprising a staple forming surface, wherein said anvil is moveably coupled to said frame between an open position and a closed position； a staple cartridge, comprising a cartridge body comprising a plurality of staple cavities and a plurality of staples removably positioned within said staple cavities, a first cam movable relative to said first end and a second cam movable relative to said second end, wherein the movement of said first cam relative to said first end and said second cam relative to said second end transitions said anvil between said open position and said closed position.
