FERNANDEZ-BOLANOS GUZMAN, José María,MAYA CASTILLA, Inés,GONZALEZ BENJUMEA, Alejandro
申请号：
ES20170000241
公开号：
ES2690412(A2)
申请日:
2017.03.10
申请国别(地区):
西班牙
年份:
2018
代理人:
摘要：
The invention can be used to double the yield of a Krapcho reaction by means of which oleacein is obtained from oleuropein, present in olive leaves. Oleacein, a dialdehyde secoiridoid present in virgin and extra virgin olive oil, has very interesting biological properties, such as anti-inflammatory and anti-asthmatic properties. For the first time, the Krapcho reaction has been extended to the conversion of monoaldehyde aglycones of oleuropein and ligstroside, present in phenolic extracts of EVOO, into the corresponding oleacein and oleocanthal dialdehyde derivatives, thereby providing a very effective method for enriching phenolic extracts with dialdehyde secoiridoids, with high added value. The invention also relates to a new method for stabilising and increasing the bioavailability of oleacein and oleocanthal using acylation and acetylation reactions. In terms of production, the invention falls within the scope of the agriculture, food, chemical and pharmaceutical fields. The invention is suitable for use
