DRAGET, KURT INGAR,ENGELSEN, STEINAR JOHAN,SETERNES, TORE,HATTREM, MAGNUS,HAUAG, INGVILD JOHANNE
申请号：
CA3023121
公开号：
CA3023121A1
申请日:
2011.10.19
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides an oral pharmaceutical composition, optionally in doseunitform, comprising a lipophilic drug substance in dispersion in aphysiologicallytolerable aqueous carrier, preferably an aqueous gel, wherein said drugsubstancecontains a functional electrostatic group having a pKa value of from 2 to 10,characterised in that said aqueous carrier has a pH at least 0.3 below orabove saidpKa value, said pH being below said pKa where said group is acidic and abovesaidpKa where said group is basic.
