MILTON, NATHANIAL,MODER, KENNETH, PHILIP,SABATOWSKI, JAMES LAWRENCE,SWEETANA, STEPHANIE ANN
申请号：
HK05109002.2
公开号：
HK1074803B
申请日:
2005.10.12
申请国别(地区):
HK
年份:
2014
代理人:
摘要：
Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
