MILTON, NATHANIAL,MODER, KENNETH, PHILIP,SABATOWSKI, JAMES LAWRENCE,SWEETANA, STEPHANIE ANN
申请号：
DK05009311
公开号：
DK1582204T3
申请日:
2000.03.02
申请国别(地区):
DK
年份:
2013
代理人:
摘要：
Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
