PROBLEM TO BE SOLVED: To provide a model animal that facilitates control of the size of swelling and the coil filling rate, minimizes the effects due to the vascular spasm and bleeding caused by indwelling procedure to the inside of the body of a non-human animal, and allows acquisition of filmed images using magnetic resonance in a short period of a few days after the indwelling, a method for producing the model animal, and also, a method for evaluating an in-vivo indwelling device that uses the model animal.SOLUTION: The model animal is used for evaluation of an in-vivo indwelling device. The model animal includes: a metallic in-vivo indwelling device 5 and a hollow body 1 made of industrial chemicals and filled with the in-vivo indwelling device. The model animal is configured such that the hollow body is disposed in a blood vessel 6 of a non-human animal or around the blood vessel. The method for producing the model animal includes: a step for preparing the metallic in-vivo indwelling device a step for preparing the hollow body made of industrial chemicals and filled with the in-vivo indwelling device and a step for disposing the hollow body in the blood vessel of the non-human animal or around the blood vessel.COPYRIGHT: (C)2013,JPO&INPIT【課題】瘤の大きさ、コイルの充填率を容易に制御でき、また非ヒト動物の体内への留置手技に伴う血管の攣縮、出血による影響を最低限に抑制し、留置後、短日数で磁気共鳴を用いた撮影画像を取得することが可能であるモデル動物を提供し、またモデル動物の作製方法を提供し、併せてモデル動物を用いた体内留置具の評価方法を提供する。【解決手段】体内留置具の評価に用いるモデル動物であって、金属製の体内留置具5と、体内留置具を充填した化成物製の中空体1とを含み、中空体が非ヒト動物の血管7又は血管周囲に配置されるモデル動物を構成した。また、金属製の体内留置具を用意する工程と、体内留置具を充填した化成物製の中空体を用意する工程と、中空体を非ヒト動物の血管又は血管周囲に配置させる工程と、を含むモデル動物の作製方法である。【選択図】 図2
