頭蓋内血管傷害非ヒト動物モデルおよびその作製方法
- 专利权人:
- 国立大学法人;東京大学
- 发明人:
- 島村 宗尚,佐田 政隆,若山 幸示,森下 竜一
- 申请号：
- JP2006324331
- 公开号：
- JP5034045B2
- 申请日:
- 2006.11.30
- 申请国别(地区):
- JP
- 年份:
- 2012
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide an animal model that has intracranial vascular injury but will not have cerebral infarction caused, and to provide a method for creating the animal model, at a high survival ratio.
SOLUTION: The method for preparing an intracranial vascular injury model in a non-human animal includes a step where occlusion thread including a nylon thread, having an epoxy resin coating layer, with an outside diameter that is insertable into the intracranial blood vessel and is capable of expanding the inserted blood vessel part, is inserted into the intracranial blood vessel under transient blood flow blockage of the non-human animal, made to detain for a prescribed time of 1-5 min and is then taken out to restart the blood flow. Although this model causes restenosis of the intracranial blood vessel but will not cause cerebral infarction to form in natural rearing, after the detaining.
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- 来源网站：
- 中国工程科技知识中心
