HANNAM UNIVERSITY INSTITUTE INDUSTRY-ACADEMIA COOPERATION;GENEWEL CO.;GENEWEL CO., LTD; LTD
发明人:
JIN-SUK CHOI,YOUNG-WOO LEE,YUN-GEE LEE,JUN-HO KIM,JIN-HO LEE
申请号：
PT09827667
公开号：
PT2366409E
申请日:
2009.09.17
申请国别(地区):
PT
年份:
2015
代理人:
摘要：
Provided is a thermosensitive composition preventing tissue adhesion and a method for preparing the same, and, more particularly, a thermosensitive composition preventing tissue adhesion which further contains a drug selectively inhibiting inflammatory response and a method for preparing the composition, in which the composition is produced through a chemical reaction by adding a cross-linking agent to an aqueous solution which contains a block copolymer containing a polyethyleneoxide block having the ability to suppress tissue adhesion, and a polymer with 10,000 to 1,000,000 g/mol of molecular weight which can be mixed with the copolymer； the composition is characterized in that the difference of viscosity, absorbance of visible rays region, and stability between the upper and lower liquid layers are within 10 % when centrifuging the composition； and also the method for preparing the composition enhances cross-linking homogenization and viscosity stability through simultaneous spraying and stirring methods without a reaction retardant.
