A method for enhancing male sexual wellness with shockwave therapy and stem cells promotes tissue repair and regeneration in or near the male penis, through the combinative effects of shockwave therapy and needle-free injection of a stem cell specimen on the penile surface of the penis. The method includes: preparing the male patient, both mentally and physically to receive stem cell therapy; applying shockwave therapy to the penis; developing a platelet-rich plasma preparation from the patient; introducing a stem cell specimen into a vial having a needle-free injector; introducing the platelet-rich plasma preparation into the vial; injecting, through the needle-free injector, the stem cell specimen and platelet-rich plasma preparation directly on penile surface from multiple positions, multiple depths, and multiple angles; reapplying shockwave therapy to the penis after a duration; and monitoring the patient for a post-procedure duration after administration of the stem cell specimen to the penis.