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PRIPREMANJE GADOBUTROLA VISOKE ČISTOĆE
专利权人:
BAYER INTELLECTUAL PROPERTY GMBH
发明人:
PLATZEK, JOHANNES,TRENTMANN, WILHELM
申请号:
RSP20200238
公开号:
RS60001B1
申请日:
2012.04.17
申请国别(地区):
RS
年份:
2020
代理人:
摘要:
A process for producing high-purity gadobutrol in a purity (according to HPLC) of more than 99.7 or 99.8 %. The process is carried out using specifically controlled crystallization conditions. The more recent developments in the field of the gadolinium-containing MR contrast agents (EP 0448191 B1. CA Patent 1341176, EP 0643705 B1, EP 0986548 B1, EP 0596586 B1) include the MRT contrast agent gadobutrol (Gadovist® 1.0) which has been approved for a relatively long time in Europe and more recently also in the USA under the name Gadavist®.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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