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Pyridone derivatives as p38α MAPK inhibitors
专利权人:
Chiyoshi Kasahara;Hitoshi Yamazaki
发明人:
Chiyoshi Kasahara,Hitoshi Yamazaki
申请号:
US12597926
公开号:
US08173684B2
申请日:
2008.05.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound represented by the formula (I): wherein R1 is lower alkyl, cycloalkyl or aromatic hydrocarbon ring, each of which is optionally substituted with one or more substituents; R2 is hydrogen atom, halogen atom, lower alkyl, halo(lower)alkyl or lower alkoxy; and R3 is (1) a group represented by the formula: wherein R4 is lower alkyl, etc.; (2) a group represented by the formula: wherein R5 is lower alkyl, etc.; (3) a group represented by the formula: wherein R6 is lower alkyl, etc.; or (4) a group selected from halogen atom, carboxy, hydroxy and lower alkoxy, or a salt thereof.
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