Composition for inducing proliferation or accumulation of regulatory T cells

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专利权人:

The University of Tokyo

发明人:

Honda Kenya,Atarashi Koji,Itoh Kikuji,Tanoue Takeshi

申请号：

US201715730203

公开号：

US10092603(B2)

申请日:

2017.10.11

申请国别(地区):

美国

年份:

2018

代理人:

Wolf, Greenfield & Sacks, P.C.

摘要：

It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/