MICKLE TRAVIS,GUENTHER SVEN,BERA SANJIB,BERA BINDU,KANSKI JAROSLAW,MARTIN ANDREA K
申请号：
IN201747018363
公开号：
IN201747018363A
申请日:
2017.05.25
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The presently described technology provides compositions comprising aryl carboxylic acids and for example NSAIDs chemically conjugated to oxycodone (4 5 a epoxy 14 hydroxy 17 methylmorphinan 6 one) to form novel prodrugs/compositions of oxycodone including benzoates salicylates propionates fenamates and acetates which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients pharmaceutical kits and methods of synthesizing conjugates of the present technology.
