Pro-Inflammatory and Adjuvant Functions of Toll-Like Receptor 4 Antagonists

• 收藏
• 分享

专利权人:

Children's Medical Center Corporation

发明人:

Jonathan C. Kagan

申请号：

US15543165

公开号：

US20180318414A1

申请日:

2016.01.12

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides methods and compositions for specific activation of inflammatory responses in dendritic cells (DCs). 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphorylcholine (PAPC) and its oxidized variant (oxPAPC) were identified to promote DC-mediated immunity, and are provided as adjuvants in immunostimulatory compositions, including vaccines.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/