The present invention relates to the Compounds and methods fors for the treatment of cancer. Specifically, the present invention provides the compound for inhibiting aurora kinase, the pharmaceutical composition including these compounds and the method using these compound treating cancers.本發明涉及治療癌症的化合物和方法。具體而言,本發明提供抑制極光激酶的化合物、包括這些化合物的藥物組合物以及使用這些化合物治療癌症的方法。