Amid N,N-bis-(2-hydroksyetylo)glyciny jako łącznik w prolekach sprzężonych z polimerem

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专利权人:

Ascendis Pharma A/S

发明人:

VETTER, DIRK,RAU, HARALD,WEGGE, THOMAS,HERSEL, ULRICH

申请号：

PL06777407

公开号：

PL1909845T3

申请日:

2006.06.21

申请国别(地区):

PL

年份:

2013

代理人:

摘要：

A polymeric prodrug is described which comprises at least one polymer attached via at least one permanent bond to a bicine linker. The bicine linker is attached via a temporary linkage to an amine containing biologically active moiety. The amine containing biologically active moiety&mdash；such as a drug&mdash；can be released by cleaving the temporary linkage.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/