PROBLEM TO BE SOLVED: To provide a composition comprising nanoparticles of a hydrolysable silicon-containing material for use as a delivery system for a bioactive ingredient.SOLUTION: The composition comprising nanoparticles of a hydrolysable silicon-containing material for use as a delivery system for a bioactive ingredient is provided in which the surface of the silicon-containing material is associated with a stabilizing agent which modifies the rate of hydrolysis of the silicon-containing material and/or inhibits the rate of orthosilicic acid polymerization. A method of promoting a controlled release of orthosilicic acid on degradation of the composition comprising nanoparticles of a hydrolysable silicon-containing material is also provided which involves the treatment of the surface of the silicon-containing material with a stabilizing agent to modify the rate of hydrolysis of the silicon-containing material and/or inhibit the rate of orthosilicic acid polymerization.【課題】生物活性成分の送達系として用いるための、加水分解性のシリコン含有物質のナノ粒子を含む組成物の提供。【解決手段】シリコン含有物質の表面はシリコン含有物質の加水分解速度を変え、かつ／あるいは、オルトケイ酸の重合速度を抑制する安定化剤と連結する組成物、ならびに加水分解性のシリコン含有物質のナノ粒子を含む組成物の分解時にオルトケイ酸の徐放を促進する方法であって、シリコン含有物質の加水分解速度を変え、かつ／あるいは、オルトケイ酸の重合速度を抑制すべくシリコン含有物質の表面の安定化剤での処理する方法。【選択図】なし
