FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to the field of organic chemistry, namely to novel derivatives of pyrazole pyridine of formula , as well as to its tautomers, geometrical isomers, enantiomers, diastereomers, racemates and pharmaceutically acceptable salts, where G1 represents H； G2 represents -CHR1R2； R1 and R2 independently on each other are selected from H； C1C6-alkoxy-C1C6-alkyl； C1-C6-alkyl； optionally substituted phenyl； optionally substituted phenyl-C1-C6-alkyl； optionally substituted morpholine-C1-C6-alkyl； or -CHR1R2 together form a ring, selected from an optionally substituted C3-C8-cycloalkyl and substituted piperidine； G3 is selected from an optionally substituted C1C6-alkoxy -C1-C6-alkyl； C1-C6-alkyl； substituted phenyl； substituted phenyl-C1C6-alkyl； G4 is selected from a substituted acyl-C1C6-alkyl, where acyl represents a group -CO-R and R stands for H or morpholine； optionally substituted C1-C6-alkyl； optionally substituted phenyl or indene； substituted phenyl-C1-C6-alkyl； optionally substituted pyridine- or furanyl-C1C6-alkyl； morpholine- or piperidine-C1-C6-alkyl； G5 represents H； where the term "substituted" stands for the groups, substituted with 1 to 5 substituents, selected from the group, which includes a "C1-C6-alkyl," "morpholine", "C1-C6-alkylphenyl", "di-C1-C6-alkylamino", "acylamino", which stands for the group NRCOR", where R represents H and R" represents a C1-C6-alkyl, "phenyl", "fluorine-substituted phenyl", "C1-C6-alkoxy", "C1-C6-alkoxycarbonyl", "halogen". The invention also relates to a pharmaceutical composition based on the formula (I) compound and particular compounds.EFFECT: obtained are the novel derivatives of pyrasole pyridine, useful for the treatment and/or prevention of disorders or states, associated with NADPH-oxidase.12 cl, 3 tbl, 21 exИзобретение относится к области органической химии, а именно к новым производным пиразолопиридина формулы (I), а также к его таутомерам, геометрическим изом
