Compositions of tigecycline and uses thereof

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专利权人:

University Health Network

发明人:

Schimmer, Aaron D.,Jitkova, Ioulia

申请号：

AU2012327237

公开号：

AU2012327237A1

申请日:

2012.12.03

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2012327237A120130620.pdf#####ABSTRACT OF THE DISCLOSURE Compositions for stabilizing tigecycline are provided, the compositions including one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester 5 thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. Compositions of stabilized tigecycline are also provided comprising tigecycline and one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. The compositions can also include a cyclodextrin. Methods of preparing, 10 uses and kits are also provided. 63

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