Dimiter S. Dimitrov,Yang Feng,John M. Maris,Zhongyu Zhu,Robyn Tovah Sussman
申请号：
US15747620
公开号：
US20180214568A1
申请日:
2016.07.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The identification and characterization of two fully human CD56-specific monoclonal antibodies targeting spatially separated epitopes proximal and distal to the plasma membrane is described. Also described are antibody-drug conjugates (ADCs) of the identified antibodies and their use for targeting CD56-expressing tumor cells.
