The present invention relates to a self-injection mechanism that causes a solution (2) having predetermined efficacy to permeate the skin (1) for skin improvement and beauty treatment. The present invention includes: an accommodation unit (10) having a space (11) therein for accommodating the solution (2), an inlet (12) which sucks only air at one end, and an outlet (15) which is open so that the solution (2) is discharged at the other end a pumping unit (20) coupled to the outlet (15) of the accommodation unit (10) so as to be in communication with the same, having an airless pump (21) which discharges the solution (2) by an up and down movement at the center and an injection unit (30) coupled with the airless pump (21) of the pumping unit (20) so as to be in communication with the same, causing the solution (2) which is discharged by the up and down movement to permeate the skin (1). The present invention can be formed into a stamp-type simple structure in order to reduce manufacturing costs, and thus can be used easily and conveniently at home at inexpensive cost. Also, the solution can be injected directly and uniformly by a needle penetrating the outer skin layer and the thick skin layer of the skin so as to minimize loss of the solution while maximizing the efficacy thereof.
