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STABILISIERTE ÜBERSÄTTIGTE TRANSDERMALE THERAPEUTISCHE MATRIXSYSTEME
专利权人:
LTS LOHMANN Therapie-Systeme AG
发明人:
MÜLLER, Walter
申请号:
EP01936058.5
公开号:
EP1263417B1
申请日:
2001.03.05
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A transdermal therapeutic system of the matrix type, comprising an active substance-impermeable backing layer, a detachable protective layer and an active substance-containing matrix based on hydrophobic polymers, the active substance having a melting point above room temperature and being present at least during part of the application time of the TTS in a concentration exceeding the saturation solubility, is characterized in that a polyacrylate polymer is admixed to the hydrophobic base polymers of the active substance matrix, or/and in that the matrix layer containing the hydrophobic polymers is provided with a self-adhesive skin-contact layer based on polyacrylates.
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