Methods of treating cancers with HER3 and PIK3CA antisense oligonucleotides

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专利权人:

Santaris Pharma A/S

发明人:

Zhang, Yixian,Qu, Zhengxing,Greenberger, Lee M.

申请号：

AU2011329180

公开号：

AU2011329180A1

申请日:

2011.11.14

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

One aspect of the invention provides methods for treating hyperproliferative disorders such as cancers in a mammal using a combination of antisense oligomers directed against HER3 and PIK3CA. Cancers treatable according to the invention include those resistant to treatment with one or more protein tyrosine kinase inhibitors. Also provided are pharmaceutical compositions including the antisense oligomers.

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中国工程科技知识中心

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http://www.ckcest.cn/home/