The present disclosure relates to patient-specific bone implants and methods for designing and making such implants. A method includes obtaining an image of a bone having an injured, diseased, or degenerative portion； determining in the image the margins at each end of the injured portion of the bone； transforming the image into a three-dimensional model； conducting a virtual surgery to remove the injured portion of the bone and create a virtual bone gap in the image； designing a patient-specific implant to fit the virtual bone gap, wherein the designed implant includes a framework having a porosity sufficient to allow blood entry through the framework and having mechanical properties similar to that of bone； and fabricating an implant based on the designed implant. Optionally, bone regeneration material is placed within the framework.
