WILEY, BENJAMIN,YANG, FEICHEN,GALL, KENNETH,RIBOH, JONATHAN
申请号：
CA3080144
公开号：
CA3080144A1
申请日:
2018.11.07
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Artificial cartilage materials for repair and replacement of cartilage (e.g., load-bearing, articular cartilage). The artificial cartilage materials described herein include triple-network hydrogels including a cross-linked fiber network (e.g., a bacterial cellulose nanofiber network) and a double-network hydrogel (e.g., a double-network hydrogel including polfacrylamide-methyl propyl sulfonic acid). The artificial cartilage may be coated onto or formed into an implant (e.g., plug). The artificial cartilage may include a surface macroporosity, e.g., 0.1-300 micrometers diameter. Also described herein are methods of forming and methods of using the triple-network hydrogel artificial cartilage materials.
