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Biological bypass bridge with sodium channels, calcium channels and/or potassium channels to compensate for conduction block in the heart
专利权人:
Michael R Rosen
发明人:
Michael R Rosen,Peter R. Brink,Ira S. Cohen,Richard B Robinson,Peter Danilo, Jr.
申请号:
US11490760
公开号:
US08236296B2
申请日:
2006.07.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides a bypass bridge comprising a tract of gap junction-coupled cells having a first end and a second end, both ends capable of being attached to two selected sites in a heart so as to allow the conduction of a pacemaker and/or electrical signal/current across the tract between the two sites, wherein the cells functionally express a sodium channel. The invention also provides related methods of making the bypass bridge, methods of implanting same in a heart, and methods of treating a disorder associated with an impaired conduction in a subjects heart.
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中国工程科技知识中心
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