A shaft assembly (200) is provided for interconnecting at least one rotatable drive shaft (212) of a hand-held electromechanical surgical device (10), and an end effector (400) actuatable by an axial drive force. The shaft assembly includes a flexible drive cable (242) rotatably supported in an outer tube (210), the flexible drive cable includes a proximal end (242a) operatively connected to a respective rotatable drive shaft (212) of the hand-held surgical device. The flexible drive cable being off set a radial distance (B vs. X) from a central longitudinal axis (X) of the outer tube. The shaft assembly includes an articulation rod (278) at least partially slidably supported in the outer tube, and an articulation link (240) having a proximal end (240a) pivotally connected to the distal end (278b) of the articulation rod (278) and a distal end (240b) pivotally connected to a distal neck housing (236). The articulation rod being off set a radial distance from the central longitudinal axis (X) of the outer tube.