THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS HEALTHCARE SYSTEM
发明人:
WANG, MINGXING,LU, QILONG,WU, BO,LU, PEIJUAN
申请号：
CA2848740
公开号：
CA2848740A1
申请日:
2012.09.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Amphiphilic cationic polymers comprising a biocompatible amphiphile linked to an organic cation are provided. The polymers complex with therapeutic agents and facilitate delivery of such therapeutic agents, particularly therapeutic nucleic acids, both in vitro and in vivo. Accordingly, the invention further provides methods of facilitating delivery of therapeutic and/or diagnostic agents to a cell and methods of treating a condition, such as a disease or infection, in an organism using the amphiphilic cationic polymers of the invention.
