Jingrong J. CUI,Yishan LI,Evan W. ROGERS,Dayong ZHAI,Wei DENG,Zhongdong HUANG
申请号:
US15745915
公开号:
US20180325901A1
申请日:
2016.07.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S13R)-11-fluoro-7,13-di-methyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo [4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclosure also relates to compositions including such compounds, and to methods of using such compositions in the treatment of diseases in mammals, especially in humans.