DAYONG ZHAI,EVAN W. ROGERS,JINGRONG JEAN CUI,WEI DENG,YISHAN LI,ZHONGDONG HUANG,EVAN W ROGERS,ZHONGDONG
申请号：
BR112018001065
公开号：
BR112018001065A2
申请日:
2016.07.20
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S13R)-11-fluoro-7,13-di-methyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo [4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclosure also relates to compositions including such compounds, and to methods of using such compositions in the treatment of diseases in mammals, especially in humans.
