Aziende Chimiche Riunite Angelini Francesco A.C.R. A.F. S.P.A.
发明人:
Maria Alessandra ALISI,Nicola Cazzolla,Barbara Garofalo,Guido Furlotti,Gabriele Magaro',Rosella Ombrato,Francesca Mancini,Gabriele Magaro
申请号:
US14825261
公开号:
US20160045485A1
申请日:
2015.08.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the new use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3β-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.