AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
发明人:
Maria Alessandra ALISI,Nicola Cazzolla,Patrizia Dragone,Guido Furlotti,Caterina Maugeri,Rosella Ombrato,Francesca Mancini
申请号:
US15439172
公开号:
US20170157121A1
申请日:
2017.02.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3β-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.