An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.本發明公開了一種穿心蓮萃取物,包含穿心蓮內酯、14-去氧穿心蓮內酯、14-去氧-11,12去氫-穿心蓮內酯和新穿心蓮內酯、多糖和黃酮類化合物。還公開了一種含有上述穿心蓮萃取物的藥學組合物以及其用於治療炎性腸病的用途。