Mohammed Abdul Raheem,Gamini Weeratunga,Carlos Zetina-Rocha,Eduardo Gustavo Cammisa
申请号:
US13997424
公开号:
US08952154B2
申请日:
2011.12.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
There is provided processes for preparing Lapatinib and pharmaceutically acceptable salts thereof by the reductive amination of the aldehyde of Formula II by treatment with 2-methanesulphonylethylamine followed by catalytic hydrogenation in the presence of a suitable hydrogenation catalyst.