SMITH, PATRICK F.,史密斯 派翠克,CHU, TOM W.,朱 汤姆,朱 湯姆,HAMMOND, JANET,汉蒙得 珍奈特,漢蒙得 珍奈特,史密斯 派翠克,朱 汤姆,朱 湯姆,汉蒙得 珍奈特,漢蒙得 珍奈特
申请号：
TW102120627
公开号：
TW201402133A
申请日:
2013.06.11
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
Embodiments disclosed in the present application relate to a composition that can include a hepatitis C viral nucleoside polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof, a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof, and a hepatitis C viral non-nucleoside polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof. Additional embodiments disclosed relate to methods for treating a disease condition such as a hepatitis C virus infection, liver fibrosis and/or impaired liver function with a hepatitis C viral nucleoside polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof, a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof, and a hepatitis C viral non-nucleoside polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof.本申請案所揭示之具體例係關於一組成物，其可包括一C型肝炎病毒核苷聚合酶抑制劑，或其醫藥上可接受之鹽或前藥，C型肝炎病毒蛋白酶抑制劑，或其醫藥上可接受之鹽或前藥，及C型肝炎病毒非-核苷聚合酶抑制劑，或其醫藥上可接受之鹽或前藥。另外所揭示之具體例係關於以C型肝炎病毒核苷聚合酶抑制劑，或其醫藥上可接受之鹽或前藥，C型肝炎病毒蛋白酶抑制劑，或其醫藥上可接受之鹽或前藥，及C型肝炎病毒非-核苷聚合酶抑制劑，或其醫藥上可接受之鹽或前藥，來治療，例如C型肝炎病毒感染、肝纖維化及/或肝功能損傷之疾病症狀的方法。
