A compound 5 - (4 - 2-cyclopropyl-1 - 1H imidazol-1-yl) - N - [6 - (4 - isopropyl - 4h-1,2,4-triazole - 3 - il) pyridin-2-yl) - 2 - fluoro 4-methylbenzamide or its Salts, such as regulating the Kinase Inhibitors apoptotic Signal； Intermediate Compounds, Pharmaceutical Composition and its use for the treatment of e Chronic renal epizootic, diabetic nephropathy, renal fibrosis, among others.
The present invention relates to a compound of formula (I): The compound has apoptosis signal-regulating kinase (&ldquo；ASK1&rdquo；) inhibitory activity, and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis.EL COMPUESTO 5-(4-CICLOPROPIL-1H-IMIDAZOL-1-IL)-N-(6-(4-ISOPROPIL-4H-1,2,4-TRIAZOL-3-IL)PIRIDIN-2-IL)-2-FLUORO-4-METILBENZAMIDA COMO INHIBIDOR DE LA QUINASA 1 REGULADORA DE LA SEÑAL DE APOPTOSIS (ASK1), COMPOSICIONES FARMACEUTICAS QUE LO COMPRENDEN, COMPUESTOS INTERMEDIOS Y USO DEL MISMO PARA PREPARAR UN MEDICAMENTO UTIL PARA EL TRATAMIENTO DE LA ENFERMEDAD RENAL CRONICA, LA NEFROPATIA DIABETICA, LA FIBROSIS RENAL, LA FIBROSIS HEPATICA, LA FIBROSIS PULMONAR Y LA ENFERMEDAD RENAL DIABETICA.
