An orthopedic cast cover is provided. The present cast cover provides a removable, sleeve-like device that securely fits over an orthopedic cast to protect skin, clothing, furniture, and other articles from being damaged by the hard, abrasive surface of a plaster or fiberglass orthopedic cast. The present cast cover may further be padded to add an additional layer of protection to the cast cover. The distal end of the cast cover is adapted to fit over the users hand protruding from the body of the cast and thereby firmly secure it in place. The present invention also has a removable flap or window portion that allows the cast being covered by the present invention to be accessed for activities such as cast signing.
