Novel compositions including bepotastine besilate are provided such as sorbitol-free compositions, compositions including at least about 0.008% w/v benzalkonium chloride, and compositions including hydroxypropylmethyl cellulose E15 LV.L'invention concerne de nouvelles compositions comprenant du bésilate de bépotastine, notamment des compositions sans sorbitol, des compositions comprenant au moins 0,008 % environ p/V de chlorure de benzalkonium, et des compositions comprenant de l'hydroxypropylméthylcellulose E15 LV.