BERDINI, VALERIO,BUCK, ILDIKO MARIA,DAY, JAMES EDWARD HARVEY,GRIFFITHS-JONES, CHARLOTTE MARY,HEIGHTMAN, THOMAS DANIEL,HOWARD, STEVEN,MURRAY, CHRISTOPHER WILLIAM,NORTON, DAVID,O'REILLY, MARC,WOOLFORD,,OREILLY, MARC,WOOLFORD, A
申请号:
CA3001799
公开号:
CA3001799A1
申请日:
2016.10.20
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2 kinases and will be useful in the treatment of ERKl/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the treatment of cancer.