BLAKE, JAMES F.,HAAS, JULIA,KOLAKOWSKI, GABRIELLE R.,ANDREWS, STEVEN W.
申请号：
CA3056754
公开号：
CA3056754A1
申请日:
2018.03.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Methods for inhibiting a ROS1 kinase with compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein. The compounds and methods provided herein are useful in the treatment of cancer (e.g., ROS1-associated cancers as defined herein).
