A method for the in vivo re-calibration of a force sensing probe such as anelectrophysiology catheter provides for the generation of an auto zero zone.The distal tip of thecatheter or other probe is placed in a body cavity within the patient.Verification that there is notissue contact is made using electrocardiogram (ECG) or impedance data,fluoroscopy or other real-time imaging data and/or an electro-anatomical mapping system. Onceverification that there is notissue contact is made, the system recalibrates the signal emanating from theforce sensor setting itto correspond to a force reading of zero grams and this recalibrated baselinereading is used togenerate and display force readings based on force sensor data. Location databased on informationprovided by a location sensor for these auto zero zone locations is stored insystem memory.During a procedure the probe may be placed in this auto zero zone for re-calibration or may beautomatically recalibrated if it is found to be in an auto zero zone at anytime.
