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LYOPHILIZED DRUG BOTULOTOXIN
专利权人:
МЕДИ-ТОКС ИНК. (KR)
发明人:
ДЗУНГ Хиунг Хо (KR),ЯНГ Ги Хиеок (KR),РХЕЕ Чанг Хоон (KR),КИМ Хак Воо (KR),КИМ Сунг Бум (KR),БАЕК Сеунг Хван (KR)
申请号:
RU2013148119/15
公开号:
RU2013148119A
申请日:
2012.03.30
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A pharmaceutical lyophilized preparation, including: botulinum toxin, polysorbate and methionine; iodine or more components selected from the group consisting of sugar, sugar alcohol, and an ionic compound. 2. The pharmaceutical lyophilized preparation according to claim 1, wherein the botulinum toxin is selected from the group consisting of Botulin Serotypes A, B, C, D, E, F and G.3. The pharmaceutical lyophilized preparation according to claim 1, wherein the botulinum toxin is a form without a complexing protein or a complex form with a complexing protein. The pharmaceutical lyophilized preparation according to claim 1, wherein the polysorbate is any one of the polysorbates 20, 40, 60, 80 and 100.5. The pharmaceutical lyophilized preparation according to claim 1, wherein the polysorbate is included in an amount of from 0.01 to 2 mg relative to 100 units of botulinum toxin. The pharmaceutical lyophilized preparation according to claim 1, wherein the methionine is included in an amount of from 0.01 to 10 mg relative to 100 units of botulinum toxin. The pharmaceutical lyophilized preparation according to claim 1, wherein the sugar is one or more selected from the group consisting of trehalose, sucrose, maltose, fructose, raffinose, lactose and glucose. The pharmaceutical lyophilized preparation according to claim 1, wherein the sugar is included in an amount of from 0.1 to 50 mg relative to 100 units of botulinum toxin. The pharmaceutical lyophilized preparation according to claim 1, wherein the sugar alcohol is one or more selected from the group consisting of cyclodextrin, mannitol, sorbitol, glycerol, xylitol and inositol. The pharmaceutical lyophilized preparation according to claim 1, wherein the sugar alcohol is included in an amount of from 0.1 to 50 mg relative to 100 units of botulinum toxin. Farm1. Фармацевтический лиофилизированный препарат, включающий:ботулотоксин, полисорбат и метионин; иодин или более компонентов, выбранных из группы, состоящей из са
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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