The present invention relates to a composition comprising a mixture which comprises or, alternatively, consists of an effective amount of colostrum and at least one pharmaceutical grade additive, said composition being for use in the treatment of pathologies of the urinary system. In particular, the present invention relates to said composition for use in the treatment of chronic pelvic pain, in particular cystitis and more preferably interstitial cystitis. The present invention relates to a composition comprising a mixture which comprises or, alternatively, consists of the following components: a) colostrum; b) chondroitin sulphate, or the salts thereof, and, optionally, c) salicin, said composition further comprises at least one pharmaceutical or food grade additive. The present invention relates to a medical device comprising said composition.