The United States of America; as represented by the Secretary Department of Health and Human Services
发明人:
Qin, Haiying,Mackall, Crystal L.,Fry, Terry J.
申请号：
AU2018269194
公开号：
AU2018269194A1
申请日:
2018.05.15
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
An embodiment of the invention provides bicistronic chimeric antigen receptor (CAR) amino acid constructs. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CAR constructs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. Methods of making the CAR constructs are disclosed.
