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compositions comprising short bioactive peptides for cellular and immunological modulation
专利权人:
Helix Biomedix Inc.
发明人:
Lijuan Zhang,Scott M. Harris,Timothy J. Falla
申请号:
BRPI0720874
公开号:
BRPI0720874B1
申请日:
2007.12.27
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
Peptide with 13 points of 56 minutes residues discloses a kind of with biological activity. These peptides account for peptide HB-107 (SEQ short fragment sequence numbers: 1), the antibacterial protein cecropin B of itself segment, and put on display stimulation cell, migration and anti-inflammatory property. When keratinocyte is especially sensitive with this meaning, disclosed peptide includes beneficial agents medical injury skin, from such as diabetic ulcer. The peptide also effectively prevents and reversing skin surface damage is due to various environments. Importantly, therapeutic effect is obvious, the concentration of peptide is equal to or more than those peptides HB-107, and therefore indicates the method exploitation effectively treatment that a tiny bit is expensive, more general. The preparation and application of these peptides is also disclosed..
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